HOME ABOUT CONTACT AVAILABLE ISSUES SUBSCRIBE MEDIA & ADS
LATEST UPDATES » Vol 22, No 04, April 2018 – Digestive health in the 21st century - Trust your guts       » Food wasted in China could feed 30-50 million       » Chinese scientists analyze human brain's "CPU"       » $150,000 fundraiser launched to sequence South Asian genomes       » Green tea-based drug carriers improve cancer treatment       » Scientists grow liver cancer cells in lab      
BIOBOARD - EUROPE
Radioembolization using sir-spheres significantly improves overall survival for patients with inoperable colorectal cancer
The results of a matched-pair comparison of patients with metastatic colorectal cancer predominately affecting the liver, for whom all chemotherapy options had been exhausted, showed that the addition of radioembolization using SIR-Spheres significantly prolonged survival compared with best supportive care (BSC) alone.1

The study, published in Cardio-vascular and Interventional Radiology, showed that median overall survival was more than doubled in patients receiving radioembolization plus BSC versus BSC alone: 8.3 months vs. 3.5 months (hazard ratio [HR] 0.26; 95% confidence interval 0.15–0.48; P<0.001). A multivariate analysis confirmed that radioembolization was the only significant predictor for prolonged survival among all the baseline parameters investigated (HR 0.30; 95% CI 0.16–0.55; P<0.001).

“Radioembolization significantly prolonged overall survival compared with supportive care alone in a well-matched cohort of patients with extensive, liver-dominant chemotherapy refractory disease for whom there are limited treatment options,” said Prof. Jens Ricke, Director of Radiology and Nuclear Medicine at the University Hospital of Magdeburg, Germany, and senior author of the study. “The evidence suggests that radioembolization should be considered as a treatment option for patients with liver-only or liver-dominant colorectal metastases who have failed or are intolerant of chemotherapy.”

References:

Seidensticker R, Denecke T, Kraus P et al. Matched-pair comparison of radioembolization plus best supportive care versus best supportive care alone for chemotherapy refractory liver-dominant colorectal metastases. Cardiovascular and Interventional Radiology 2012; 35(5): 1066–1073.

International Agency for Research on Cancer. GLOBOCAN 2008: Colorectal Cancer Incidence and Mortality Worldwide in 2008. https://globocan.iarc.fr/factsheets/cancers/colorectal.asp accessed 12/8/2011.

Click here for the complete issue.

NEWS CRUNCH  
news Shire, Microsoft and EURORDIS form Global Commission to accelerate time to diagnosis for children with rare diseases
news EmTech Asia explores future of life, humanity and economy
news Biology of Ageing II - Impactful Interventions
PR NEWSWIRE  
Asia Pacific Biotech News
EDITORS' CHOICE  
COLUMNS  
Subscribe to APBN E-Newsletter
Find us under 'Others' option to receive APBN e-newsletters thrice a month!

APBN Editorial Calendar 2018
January:
Obesity / Outlook for 2018
February:
Searching for the fountain of youth
March:
Women in Science - Making a difference
April:
Digestive health in the 21st century - Trust your guts
May:
Asthma / Dental health
June:
Oncology / Biotech landscape in APAC
July:
Water management / Vaccination
August:
Regenerative medicine / Biotech start ups
September:
Digital healthcare / 3D printing
October:
Bones / Breast cancer
November:
Liver health / Top science research nations & institutions
December:
AIDS / Breakthrough of the year/Emerging trends
Editorial calendar is subjected to changes.
MAGAZINE TAGS
About Us
Events
Available issues
Editorial Board
Letters to Editor
Instructions to Authors
Advertise with Us
CONTACT
World Scientific Publishing Co. Pte. Ltd.
5 Toh Tuck Link, Singapore 596224
Tel: 65-6466-5775
Fax: 65-6467-7667
» For Editorial Enquiries:
   biotech_edit@wspc.com or Ms Lim Guan Yu
» For Subscriptions, Advertisements &
   Media Partnerships Enquiries:
   biotech_ad@wspc.com
Copyright© 2018 World Scientific Publishing Co Pte Ltd  •  Privacy Policy