HOME ABOUT CONTACT AVAILABLE ISSUES SUBSCRIBE MEDIA & ADS CONFERENCE CALENDAR
LATEST UPDATES » Volume 20, Volume 2, February 2016 Biomedical Research Governance       » Tissue banking in Singapore — An Evolving Enterprise       » China Recognizes Prominent Scientists and Stresses on Innovation       » NUS Researchers Uncover Potent Parasite-killing Mechanism of Nobel Prize-Winning Anti-Malarial Drug       » A New Water Robot "Born" to Detect Water Quality       » Probing the Mystery of How Cancer Cells Die       » Researchers Find Link between Processed Foods and Autoimmune Diseases       » Unravelling the Genetics of Pregnancy and Heart Failure      
EYE ON CHINA
New analytical method for uleine alkaloids having anticancer activity
Two uleine alkaloids were isolated from the trunk bark of Winchia calophylla which exhibited anticancer activity. Their potential applications in clinical experiments necessitate the development of a new method for the analysis of uleine alkaloids.

In order to establish a reliable, fast and low-cost analysis method, researchers in Prof. Wu Zhijun lab at the Chengdu Institute of Biology, Chinese Academy of Sciences investigated their structural characteristic using electrospray tandem mass spectrometry (ESI-MS/MS) method. Dr. Wu and his colleagues revealed fragmentation rules of uleine alkaloids and found that a Retro Diels Alder (RDA) reaction played a significant role in their skeletal fragmentation. The corresponding information can be used for the rapid analysis of uleine alkaloids in complex mixtures from plant extract.

The method is a rapid and new analysis method for the identification of uleine alkaloids in complex matrices and also provides a new way for their total synthesis.This research entitled “Electrospray ionization tandem mass spectrometry of uleine alkaloids” was published in Rapid Commun.Mass Spectrom. on September 19, 2012.

Click here for the complete issue.

NEWS CRUNCH  
news EmTech Asia Opens: Features 50 speakers on innovation and emerging technologies
news Russia's only project to supply local high-tech anti-cancer drugs abroad continues with the first shipment to Vietnam
news Wheat Genome Sequencing Gets Major Boost
PR NEWSWIRE  
Asia Pacific Biotech News
EDITORS' CHOICE  

Primates in Biomedical Research
COLUMNS  
\
APBN Editorial Calendar 2016
January:
Guest Editorial - Biotechnology In Korea
February:
Guest Editorial - Biomedical Research Governance
March:
Guest Editorial - Life-Saving Opportunities: A Guide to Regenerative Medicine
April:
Cancerology / Oncology
May:
Guest Editorial - Antibody Informatics In Japan
June:
Medical Devices and Technology
July:
Water Technology
August:
Occupational Health
September:
Olympics: Evolution of Sports
October:
Respiratory: Seasonal flu viruses
November:
Tobacco Smoking
Editorial calendar is subjected to changes.
– Editor: Carmen, Jia Wen Loh
MAGAZINE TAGS
About Us
Events
Available issues
Editorial Board
Letters to Editor
Instructions to Authors
Advertise with Us
CONTACT
World Scientific Publishing Co. Pte. Ltd.
5 Toh Tuck Link, Singapore 596224
Tel: 65-6466-5775
Fax: 65-6467-7667
» Editorial Enquiries: biotech_edit@wspc.com
» For Subscriptions, Advertisements &
   Media Partnerships Enquiries:
   Ms PoPo Kwok or Ms Sok Ching Lim/td>
Copyright© 2015 World Scientific Publishing Co Pte Ltd  •  Privacy Policy