HOME ABOUT CONTACT AVAILABLE ISSUES SUBSCRIBE MEDIA & ADS
LATEST UPDATES » Vol 22, No 04, April 2018 – Digestive health in the 21st century - Trust your guts       » Food wasted in China could feed 30-50 million       » Chinese scientists analyze human brain's "CPU"       » $150,000 fundraiser launched to sequence South Asian genomes       » Green tea-based drug carriers improve cancer treatment       » Scientists grow liver cancer cells in lab      
EYE in CHINA
Disruptions of functional brain connectomes in individuals at risk for Alzheimer's disease
Biological Psychiatry published a cover article reporting a cooperation research in which professor Xi-Nian Zuo from Institute of Psychology participated. Employing resting state functional Magnetic Resonance Imaging (R-fMRI) technique and graph theory in mathematics, the study conducted a systematic and intensive examination on the topological properties of human brain functional connectome with high precision in individuals at risk for Alzheimer's disease (AD) (i.e., Mild Cognition Impairment). The findings read: the disease mainly affects the functional connectivity within default network and the connectivity between advanced cognitive network module; the abnormalities of topological properties of brain connectome was significantly correlated with the memory function decline, also the abnormalities could be effectively used to distinguish patients and normal subjects (the correct prediction rate>85%). This work represents the first attempt to explore the functional networks in AD using functional connectome with higher precision (1024 nodes). The test-retest reliability of functional connetome construction method based on wavelet was systematically assessed for the first time. All these outcomes would supply valuable references for the standards on the functional connetome construction.

This high-impact journal thus launched a special issue on “Disturbances in the Connectome and Risk for Alzheimer's Disease” to report the latest progress in AD researches. Professors Arthur W. Toga and Paul M. Thompson, directors of neuroimaging laboratory of UCLA, key researchers of Human Connectome Project, were invited to write a commentary ‘Connectomics, Sheds New Light on Alzheimer's Disease’ and commented: A highly innovative study revealing how brain networks break down in AD.

Click here for the complete issue.

NEWS CRUNCH  
news Shire, Microsoft and EURORDIS form Global Commission to accelerate time to diagnosis for children with rare diseases
news EmTech Asia explores future of life, humanity and economy
news Biology of Ageing II - Impactful Interventions
PR NEWSWIRE  
Asia Pacific Biotech News
EDITORS' CHOICE  
COLUMNS  
Subscribe to APBN E-Newsletter
Find us under 'Others' option to receive APBN e-newsletters thrice a month!

APBN Editorial Calendar 2018
January:
Obesity / Outlook for 2018
February:
Searching for the fountain of youth
March:
Women in Science - Making a difference
April:
Digestive health in the 21st century - Trust your guts
May:
Asthma / Dental health
June:
Oncology / Biotech landscape in APAC
July:
Water management / Vaccination
August:
Regenerative medicine / Biotech start ups
September:
Digital healthcare / 3D printing
October:
Bones / Breast cancer
November:
Liver health / Top science research nations & institutions
December:
AIDS / Breakthrough of the year/Emerging trends
Editorial calendar is subjected to changes.
MAGAZINE TAGS
About Us
Events
Available issues
Editorial Board
Letters to Editor
Instructions to Authors
Advertise with Us
CONTACT
World Scientific Publishing Co. Pte. Ltd.
5 Toh Tuck Link, Singapore 596224
Tel: 65-6466-5775
Fax: 65-6467-7667
» For Editorial Enquiries:
   biotech_edit@wspc.com or Ms Lim Guan Yu
» For Subscriptions, Advertisements &
   Media Partnerships Enquiries:
   biotech_ad@wspc.com
Copyright© 2018 World Scientific Publishing Co Pte Ltd  •  Privacy Policy