HOME ABOUT CONTACT AVAILABLE ISSUES SUBSCRIBE MEDIA & ADS CONFERENCE CALENDAR
LATEST UPDATES » Volume 20, No. 5, May 2016 – Healthcare Systems & Policies in Asia       » Understanding Healthcare Policies in the Philippines: Cancer Care       » Young Innovators under 35       » Healthcare Cost Effectiveness in Singapore       » ASLAN Pharmaceuticals Opens China Office       » A Journey Inside the Human Body       » Treatment Brings New Hope for Patients Suffering From Fatal Lung Disease      
BIOBOARD - INSIDE INDUSTRY
Biolife Science $5m ASX listing to progress stomach & breast cancer vaccine
Australian shareholders are being given the opportunity to buy into a highly promising biotech with a vaccine that shows significant potential in the fight against stomach (gastric) and breast cancer.

Biolife Science Limited will be acquired by Perth-based Acuvax Limited. The Patersons-managed raising aims to generate up to $5 million for Phase II clinical trials of Biolife’s HER-Vaxx vaccine, which has shown significant success in stimulating the production of lifesaving HER-2 antibodies in late-stage cancer patients.

HER-Vaxx is expected to provide a natural, potentially more potent alternative to Roche’s popular injectable antibody, Herceptin®, which has become one of the world’s best-selling cancer drugs with sales of $US6.4 billion in 2012. Metastatic breast cancer patients in Biolife’s Phase I study developed HER-2 antibodies that produced potent anti-tumour activity, thus inducing an antibody response with similar anti-tumour properties to Roche’s Herceptin® and effectively turning the patient’s body into a “Herceptin® factory”.

An Investigational New Drug (IND) application is expected to be filed with the FDA Q3, 2013 and Biolife has already appointed a leading Swiss vaccine producer Pevion Biotech AG to manufacture the HER-Vaxx vaccine. This will be ready for the commencement of the subsequent Phase II clinical study.

The incoming management team includes seasoned biotechnology executives and company builders Dr. Roger Aston and Mr Paul Hopper as well as a Scientific Advisory Board that includes several of the inventors.

Dr. Aston has held leadership roles with ASX listed companies Peptech, Cambridge Antibody, Clinuvel, pSivida and Mayne Pharma. Mr Hopper is Head of the Life Sciences Desk of US investment bank Cappello Capital Corp and is a director of ASX listed Viralytics and pSivida. Both have extensive experience developing vaccines, undertaking clinical trials and marketing products.

Director elect, Dr. Axel Hoos, will also be joining the Board. Dr. Hoos is Vice President, Oncology R&D with GlaxoSmithKline and brings a wealth of experience in cancer drug development to Biolife.

“This is an exhilarating moment for Biolife, which can now see a new life for itself and for one of the most promising new oncology drugs to emerge in recent times,” Dr. Aston said. “We have no doubt that this represents the most expedient way forward for our shareholders, our technology, and – ultimately – for the thousands of cancer patients that stand to benefit from this highly promising vaccine.”

“Given the comparatively low levels of investment activity in Europe, the opportunity has arisen to progress this ground-breaking vaccine with Australian funds for clinical studies in Europe and possibly also in Australia.”

After undergoing a 200 to 1 share consolidation, Acuvax is seeking to raise up to $5 million through the placement of up to 25 million shares at $0.20 each – giving Biolife an initial market cap of $11.3 million and paving the way for the Phase II trials of HER-Vaxx following approval of an FDA IND application.

Stomach cancer and breast cancer are among the most virulent forms of cancer, killing more than 1.2 million people globally each year. The market for stomach cancer drugs alone is projected to rise to nearly $1.4 billion by 2020 – with nearly 20% of patients suffering from HER-2 positive forms of the disease. Between 25-30% of breast cancers are HER-2 positive.

Click here for the complete issue.

NEWS CRUNCH  
news World Immunisation Week 2016
news IoT Asia 2016 Delivers Actionable Solutions for a Sustainable IoT Ecosystem in Asia
news Lite-On presents a new Biomedical Research and Development Centre in Singapore
PR NEWSWIRE  
Asia Pacific Biotech News
EDITORS' CHOICE  
COLUMNS  
APBN Editorial Calendar 2016
January:
Guest Editorial - Biotechnology In Korea
February:
Guest Editorial - Biomedical Research Governance
March:
Guest Editorial - Life-Saving Opportunities: A Guide to Regenerative Medicine
April:
Leading-Edge ONCOLOGY
May:
Healthcare Systems & Policies in Asia
June:
Medical Devices and Digital Health Technology
July:
Water Technology
August:
Guest Editorial - Antibody Informatics In Japan
September:
Infectious Diseases
October:
Medical Tourism
November:
Biomedical Imaging Technology
December:
Food Technology
Editorial calendar is subjected to changes.
– Editor: Carmen, Jia Wen Loh
MAGAZINE TAGS
About Us
Events
Available issues
Editorial Board
Letters to Editor
Instructions to Authors
Advertise with Us
CONTACT
World Scientific Publishing Co. Pte. Ltd.
5 Toh Tuck Link, Singapore 596224
Tel: 65-6466-5775
Fax: 65-6467-7667
» Editorial Enquiries: biotech_edit@wspc.com
» For Subscriptions, Advertisements &
   Media Partnerships Enquiries:
   Ms PoPo Kwok or Ms Sok Ching Lim/td>
Copyright© 2015 World Scientific Publishing Co Pte Ltd  •  Privacy Policy