HOME ABOUT CONTACT AVAILABLE ISSUES SUBSCRIBE MEDIA & ADS CONFERENCE CALENDAR
LATEST UPDATES » Vol 21, No 08, August 2017 – Eye – the Window to your Soul       » Palm-Sized PCR Device for Rapid Real-Time Detection of Viruses       » Scientists Uncover New Mechanism for Diabetic Neuropathy       » China Enlists AI to Diagnose Breast Cancer       » Philips and Singapore Institute of Advanced Medicine Holdings Sign Agreement to Open First-of-its-kind Oncology Center in Singapore       » Guardian Partners with MyDoc to Address Singapore's Population Health Needs through Integrating Technology and Self-Care       » Database Boosts Shanghai's Technology Aim      
BIOBOARD - INDIA
India develops cheap rotavirus vaccine
An Indian vaccine against rotavirus — the leading cause of diarrhea-related deaths in most developing countries — promises cheap home-grown protection while adding to the global basket of rotavirus vaccines, an international team announced.

Severe diarrhea caused by rotavirus claims the lives of 453,000 under-five children worldwide each year. India tops the list, contributing to 22% of the deaths or an estimated 100,000-163,000 each year. Half of India's rotavirus-related diarrheal deaths are of less-than-a-year old infants.

The two internationally licensed oral rotavirus vaccines, GlaxoSmith Kline (GSK)'s Rotatrix and Merck's Rotatec, are priced at US$ 40 per dose, but provided at US$ 2 per dose in poor countries under an arrangement with the Global Alliance for Vaccine Initiative (GAVI).

Scientists announced in New Delhi the results of third phase of clinical trials — involving 6,799 infants in three Indian states — of Rotavac, an oral vaccine based on a strain circulating in India and developed under an Indo-US partnership.

Rotavac reduced severe rotavirus-related diarrhoea cases by 56% in infants under-one year, with protection continuing into the second year, K Vijayargahavan, secretary, Department of Biotechnology, told an international symposium.

The new vaccine protected against a broad range of rotavirus strains and can be given to infants along with oral polio vaccine, Vijayaraghavan said. “Its efficacy is comparable to that of the two licensed vaccines (from GSK and Merck) in low-resource settings.”

A Hyderabad-based firm, Bharat Biotech, is ready to offer Rotavac at US$ 1 per dose and plans to file for licensing. 

Carsten Mantel, medical officer at the WHO, said India should address the need for strengthening cold-chain facilities for storage and transport if it plans to reach out to resource-poor settings at home and in other developing countries.

The symposium was buoyed by reports from Latin America and South Africa on reduced diarrheal cases and deaths as a result of rotavirus vaccination programmes.

Since introduction of vaccination in 2007, Mexico has averted 1,000 diarrhoea deaths, 190,000 diarrhoea cases and 5,250 hospital admissions annually, said Marcelino Esparza Aguilar, medical supervisor at the National Centre for Child and Adolescent Health, Mexico City.

Brazil, which introduced vaccination in 2006, saw 1,500 fewer deaths and 130,000 fewer hospitalizations in the two following years among under-five children.

South Africa has cut diarrhoea cases in the under-one year age group by half, Nicola Page, head of the enteric diseases unit at the National Institute of Communicable Diseases, Johannesburg, said.

“Countries such as Ethiopia have had to delay vaccination programmes due to limited supply,” Kathleen Neuzel from the non-government organization, Program for Appropriate Technology in Health, told SciDev.Net. “Now, we could potentially have another rotavirus vaccine in the market.”

Source: Science Development Network

Click here for the complete issue.

NEWS CRUNCH  
news Vitafoods Asia 2017: Industry players optimistic of future
news Nestlé Introduces their Singapore R&D Centre
news Vitafoods Asia Elevates 2017 Learning Programme
PR NEWSWIRE  
Asia Pacific Biotech News
EDITORS' CHOICE  

Lady Ganga: Nilza'S Story
COLUMNS  
Subscribe to APBN E-Newsletter
Find us under 'Others' option to receive APBN e-newsletters thrice a month!

APBN Editorial Calendar 2017
January:
Healthcare Focus: LUNGS
February:
War on CANCER
March:
Get to Know TCM
April:
Diabetes: The Big Picture
May:
The Piece of Your Mind - Brain Health/Science
June:
Advocacies in Support of Rare Disease Patients
July:
Food Science & Technology
August:
Eye – the Window to your Soul
September:
Emerging Infectious Diseases
October:
No. 1 Killer — Heart Diseases
November:
Diseases threatening our Children
December:
Skin Diseases/Allergic Reactions
Editorial calendar is subjected to changes.
MAGAZINE TAGS
About Us
Events
Available issues
Editorial Board
Letters to Editor
Instructions to Authors
Advertise with Us
CONTACT
World Scientific Publishing Co. Pte. Ltd.
5 Toh Tuck Link, Singapore 596224
Tel: 65-6466-5775
Fax: 65-6467-7667
» For Editorial Enquiries:
   biotech_edit@wspc.com or Ms Carmen
» For Subscriptions, Advertisements &
   Media Partnerships Enquiries:
   biotech_ad@wspc.com
Copyright© 2017 World Scientific Publishing Co Pte Ltd  •  Privacy Policy