HOME ABOUT CONTACT AVAILABLE ISSUES SUBSCRIBE MEDIA & ADS CONFERENCE CALENDAR
LATEST UPDATES » Vol 21, No 05, May 2017 – Insights Into the Brain & microRNAs       » Omega-3 Therapy May Help Reverse Type 1 Diabetes       » The Potential of Saving Human Lives with Hibernation       » Scientists Unlock TCM Drug's Role in Weight Loss       » Medical Reforms in Beijing       » Fruits and Vegetables' Latest Superpower? Lowering Blood Pressure      
EYE ON CHINA
Innovative technique creates large skin flaps for full-face resurfacing
Patients with massive burns causing complete loss of the facial skin pose a difficult challenge for reconstructive surgeons. A group of surgeons in China have developed an innovative technique for creating a one-piece skin flap large enough to perform full-face resurfacing.

Dr. QingFeng Li and colleagues of Shanghai Jiao Tong University School of Medicine describe their approach to creating "monoblock" flaps for use in extensive face skin resurfacing. In their successful experience with five severely disfigured patients, the full-face tissue flap "provides universally matched skin and near-normal facial contour."

New technique grows one-piece skin flaps for full-face resurfacing

Complete destruction of the facial skin and underlying (subcutaneous) tissues presents "the most challenging dilemma" in facial reconstructive surgery. Multiple skin flaps and grafts are needed to provide complete coverage, creating a "patchwork" appearance. Standard skin grafts are also too bulky to provide good reconstruction of the delicate features and expressive movement of the normal facial skin.

To meet these challenges, Dr. Li and colleagues have developed a new technique for creating a single, large skin flap appropriate for use in full-face resurfacing. Their approach starts with "prefabrication" of a flap of the patient's own skin, harvested from another part of the body. The skin flap, along with its carefully preserved blood supply, is allowed to grow for some weeks in a "pocket" created under the patient's skin of the patient's upper chest.

Tissue expanders — balloon-like devices gradually filled with saline solution — are used to enlarge the skin flap over time. While skin expansion is a standard technique for creation of skin flaps, Dr. Li and his team used an "overexpansion" approach to create very large flaps of relatively thin skin — ideal for use in the facial area. In some cases, when the skin flap was growing too thin, stem cells derived from the patients' own bone marrow were used as an aid to tissue expansion.

Using this technique, Dr. Li and colleagues were able to create very large skin flaps — up to 30 X 30 cm — for use in full-face resurfacing. They used this prefabrication/overexpansion technique in five patients with complete loss of the facial skin, caused by flame or chemical burns. All patients had previously undergone facial reconstruction, but were left with severe deformity and limited facial movement.

The "monoblock" allowed the surgeons to perform complete facial resurfacing using a single flap of the patient's own skin. The large flap size avoided problems with a "patchwork" appearance, while the thin flap width was well-suited for reconstruction of the facial features.

Multiple surgeries were needed to refine the results and to manage complications. However, all five patients eventually achieved a more normal appearance and better functioning — including improved emotional expression.

The researchers emphasize that their patients with massive facial burns, while severely disfigured, differ from those with deeper tissue destruction who are candidates for face transplantation. Patients being considered for face transplantation have destruction not only of the skin and subcutaneous tissues, but also of the underlying facial muscles and organs of the head and neck.

Dr. Li and coauthors believe their technique, although complex, provides a valuable new approach to reconstruction for patients with complete destruction of the facial skin. They conclude, "It is a reliable and an excellent reconstructive option for massive facial skin defects."

Click here for the complete issue.

NEWS CRUNCH  
news Healthcare Sustainability in Asia: Now is the Time to Act — FT Asia Healthcare & Life Sciences Summit 2017
news Philip Morris International and British American Tobacco receive award from PETA science group for AOP developments
news 6th Asia-Pacific Breast Cancer Summit to take place in Hong Kong
PR NEWSWIRE  
Asia Pacific Biotech News
EDITORS' CHOICE  

Lady Ganga: Nilza'S Story
COLUMNS  
Subscribe to APBN E-Newsletter
Find us under 'Others' option to receive APBN e-newsletters thrice a month!

APBN Editorial Calendar 2017
January:
Healthcare Focus: LUNGS
February:
War on CANCER
March:
Get to Know TCM
April:
Diabetes: The Big Picture
May:
The Piece of Your Mind - Brain Health/Science
June:
Rare Diseases
July:
Food Science & Technology
August:
Eye Care/ Eye Health
September:
No. 1 Killer - Heart Diseases, Diagnosis and Treatment
October:
Skin Diseases/Allergic Reactions
November:
Diseases threatening our Children
December:
Liver Health & Treatment/Technology
Editorial calendar is subjected to changes.
– Editor: Carmen, Jia Wen Loh
MAGAZINE TAGS
About Us
Events
Available issues
Editorial Board
Letters to Editor
Instructions to Authors
Advertise with Us
CONTACT
World Scientific Publishing Co. Pte. Ltd.
5 Toh Tuck Link, Singapore 596224
Tel: 65-6466-5775
Fax: 65-6467-7667
» For Editorial Enquiries:
   biotech_edit@wspc.com or Ms Carmen
» For Subscriptions, Advertisements &
   Media Partnerships Enquiries:
   biotech_ad@wspc.com
Copyright© 2017 World Scientific Publishing Co Pte Ltd  •  Privacy Policy