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Molecular test to predict immunotherapy response for kidney cancer
Study was conducted using the CLEARScore test that identifies eight genes linked to immunotherapy

Immunotherapy drugs such as PD-L1 checkpoint inhibitors represent the front-line treatment for kidney cancer. But it is expensive, benefits only a subset of patients and is futile in the majority of patients.

Researchers from the National Cancer Centre Singapore and Lucence Diagnostics have conducted a study using Lucence鈥檚 molecular test, CLEARScore, to predict whether a kidney cancer patient will or will not benefit from immunotherapy thus helping to reduce futile costs and side effects.

CLEARScore is an algorithm involving eight genes in the tumour, which classifies kidney cancer by molecular type.

Kidney cancer is among the ten most common cancers in men and women across the world. In 2018, there were over 400,000 new cases of kidney cancer globally.

Previously, the test has been used to successfully predict treatment response of kidney cancer patients to tyrosine kinase inhibitors, a type of targeted therapy. The results were published in 2015 in European Urology.

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news Medial Fair Thailand opened on 11th September 2019 with a focus on future-proofing Thailand's healthcare industry to meet the challenges and opportunities of the next decade
news Biofuel Producers and Users to Convene in Singapore for Global Biofuels Summit
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LIFE OF A SCIENTIST  

APBN Editorial Calendar 2019
January:
Taiwan Medical tourism
February:
Marijuana as medicine — Legal marijuana will open up scientific research
March:
Driven by curiosity
April:
Career developments for researchers
May:
What's cracking — Antibodies in ostrich eggs
June:
Clinical trials — What's in a name?
July:
Traditional Chinese medicine in modern healthcare — Integrating both worlds
August:
Digitalization vs Digitization — Exploring Emerging Trends in Healthcare
September:
Healthy Ageing — How Science is chipping in
October:
Disruptive Urban Farming — Microbes, Plasmids, and Recycling
Editorial calendar is subjected to changes.
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