LATEST UPDATES » Vol 26, Nos. 11 & 12, November & December 2022 – Worlds Within Worlds – Viruses, Humanity, and the Environment       » Pinpointing How This Key Protein Facilitates Viral Transmission From Insects to Plants       » A New Approach to Treating Organic Wastewater       » Using Old Plants for New Tricks?       » Using Gas Bubbles as Lenses to View Tissues More Deeply       » Seawater as a Renewable Energy Source       » Generating Oxygen Within Cells
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Vol 26, Nos. 11 & 12, November & December 2022
Advancing the Digital Transformation of Biopharma ManufacturingBy Nicolas Pivet
Digitalisation can revolutionise the industry and reduce time to market by leveraging powerful tools like data and cloud infrastructure to introduce greater flexibility and efficiency in the manufacturing process.
What Has COVID Ever Done for Us?By Ivor Campbell
While COVID-19 devastated the world, what various developments in diagnostics and medical technology have occurred as a result of and in response to the pandemic?
Nudging Towards Safer Decision-Making in HealthcareBy Laís Junqueira
With complex and dynamic healthcare systems, along with an under-resourced and overburdened healthcare workforce, how can we best avoid errors and secure patient safety?
Harnessing Self-Renewing Cells for Treatment of Cartilage DamageBy Dr Yang Zheng and Prof Jongyoon Han
Osteoarthritis is an extremely common condition – causing pain in joints during walking, standing, and other activities – that afflicts many, especially the elderly; researchers are working on using mesenchymal stem cells for more effective cartilage repair to prevent the onset or progression of osteoarthritis.
The Mental Well-Being of Clinicians is a Top PriorityBy Dr MJ Erickson-Hogue
As healthcare providers around the world struggle to retain and hire staff in the midst of rising healthcare demands, how can the industry provide better support to prevent clinician burnout?
Vol 26, Nos. 09 & 10, September & October 2022
The Importance of Routine Immunisation in a Post-COVID WorldBy Dr Aileen Dualan
Immunisation is one of the most successful public health interventions but progress in the last two years has stalled or even reversed.
Leveraging AI to Tackle the Looming Metabolic Syndrome CrisisBy Robert Thong and Andrew Wu
In this article, we look at how Mesh Bio and MultiOmic Health use AI to transform and improve the lives of metabolic syndrome patients through patient stratification and precision medicine.
Making Strides Against Liver Cancer With Transformative Cellular TherapyBy Christy Ma
Cancer is one of the leading causes of death in the world and arguably the most heartwrenching. In Singapore, liver cancer is the third deadliest cancer among men and the fifth among women.
The Digitisation of Neuroscience: Democratising Brain Health for Our PopulationsBy Nav Vij and Dr Prem Pillay
Our brain is the most complex organ in the body, yet its true value to businesses and economies has yet to be fully realised. Are digital neuroscience solutions the key to ensuring our knowledge-based economies continue to thrive in the post-pandemic normal?
Immersive Virtual Reality: The Next Frontier in Surgical EducationBy Dr Chen Min Wei and Samuel Choo
How bite-sized virtual trips to the operating theatre will bridge the gap between reading about surgery and actually performing surgery.
Vol 26, Nos. 07 & 08, July & August 2022
The Way Forward Towards Management of Chronic Heart FailureBy Dr Manish Bansal
How telehealth has improved the accessibility and continuity of care for heart patients.
An Industry in Full Disruption: How Digitisation is Transforming MedTechBy Anupama Puranik, Wolfgang Bauriedel, and David Krahe
With digitisation, MedTech companies looking to stay ahead will have to rethink their approach not just to technology, but to their business models, talent, and transformation of mission and culture.
De-extinction: Satisfying Nostalgia or Rectifying Wrongs?By Vanessa Quek
Is the cause for de-extinction merely to satisfy our nostalgia or do we genuinely want to restore our planet with the diversity of flora and fauna it once had?
Vol 26, Nos. 05 & 06, May & June 2022
The Growing Burden of Uncorrected Myopia in AsiaBy Hamish Thrum
Eye care practitioners (ECPs) must incorporate myopia management into their practice right now to help reduce the burden of sight-threatening conditions in the future.
Moving From Pandemic to Endemic: Ensuring Vaccine Access to AllBy Dr Gajendra Singh
This article explores some of the challenges and solutions to drive vaccine access, including exploring different vaccine options in the market and spurring regional and international collaboration.
The Value of Medical InnovationBy Dr Rebecca Dent
The incidence of breast cancer is growing in Asia and is the most common cancer among women in the region. With medical advancements, the survival rates for breast cancer have improved over time. However, unmet needs remain for breast cancer survivors and it is important that we continue to develop new innovations and enhance patients’ access to innovative cancer drugs.
Innovation in Oncology Management, A Promising Look for PatientsBy Jennifer Cho
How artificial intelligence is paving the way for better cancer management.
Vol 26, Nos. 03 & 04, March & April 2022
Cutting-Edge Computing Tools are the Future of Genome SequencingBy Sumir Bhatia
As the world continues to grapple with the evolving variants of the COVID-19 virus, our ability to identify mutations accurately and speedily to develop the vaccines will determine how long the pandemic will continue to disrupt our lives.
Defending the Patient’s Journey in The Face of RansomwareBy Justin Loh
The healthcare industry has seen a series of cyberattacks and data breaches exacerbated by the global pandemic. How can we ensure that patient data is protected in all forms?
Vol 26, No. 02, February 2022
Injecting Trust in the Pharmaceutical Supply Chain with Technology-led TransparencyBy Tan Aik Jin
With the strong uptake of COVID-19 vaccines this year, there is a need to ensure increased stability, visibility, and transparency across the supply chain to drive resilience in these times.
Non-biological Estimate of Omicron IncidenceBy Dr Galileo Violini
A mathematical method to describe the relative weight of two infections of different transmissibility is presented and applied to discuss the incidence of Omicron and Delta in two case studies (Italy and Argentina).
Preparing for Crisis X – Not If but When By Benedict Cheong
COVID-19 has highlighted the urgency for ASEAN leaders to collaborate and strategise viable and sustainable solutions for more resilient healthcare systems to withstand future challenges. It’s not a matter of if the next pandemic will happen, but when.
Vol 26, No. 01, January 2022
Understanding the Antigen-Specificity of Host T Cells Is a Game-Changer in TransplantationBy A/Prof Alexandra Sharland, Dr Nicole Mifsud, and Eric Son
A recent study pinpoints the precise molecular targets of organ transplant rejection.
Vol 25, No. 12, December 2021
Navigating Through Current and Future Health ChallengesBy Lu-Ching Lau
With 2022 on the horizon, Lu-Ching Lau, Director for External Affairs, Policy and Communications, Singapore and Malaysia, MSD, discusses three key areas where greater cooperation between public and private sectors can create synergistic benefits.
Vol 25, No. 11, November 2021
The Tricky COVID-19 Contagion – Deaths Comparison: Worldwide and Italy AnalysisBy Dr Galileo Violini
A deeper look into Italy’s contagion data and if there is a connection between Italy’s R-value and vaccination rate.
Vol 25, No. 10, October 2021
Adeno-Associated Virus: Next-Generation Drug Delivery for Neurodegenerative DiseasesBy Vanessa Lunardi
In this article, we discuss the latest human gene therapy trials showing that delivering genes using the adeno-associated virus into the brain can effectively and durably correct the pathogenic mechanisms of neurodegeneration.
Vol 25, No. 09, September 2021
How Can We Be Better Prepared to Manage COVID-19 in Children?By Dr. Sanjay Prabhu
Dr. Sanjay Prabhu discusses how the public and healthcare professionals can better manage COVID-19 in children in anticipation of a third wave of the pandemic.
Vol 25, No. 08, August 2021
The Role of China in Future EpidemicsBy Dr. Ping-Chung Leung
An analysis of the integrative use of Traditional Chinese Medicine in managing treatment outcomes of COVID-19 patients.
Lessons From COVID-19 Vaccines – Developing Medical Therapies Does Not Need to Take DecadesBy Dr. Chris Nave
While other vaccines have taken years, COVID-19 has seen the development of COVID vaccines in under a year. What does this mean for us going forward?
Vol 25, No. 07, July 2021
Reimagining Healthcare in Asia Through Digital TherapeuticsBy Hema Thiagarajah
A rapidly ageing population, combined with a surge in chronic, non-communicable diseases is driving the rise of healthcare costs in Asia. Digital therapeutics holds immense potential to radically transform healthcare from reactive treatment to proactive, predictive prevention and management of disease.
Vol 25, No. 06, June 2021
Understanding the microbiome as the 'Gateway to Wellness'
The human microbiome is gaining increasing traction with wellness-conscious consumers around the world. Historically viewed as being on the periphery of mainstream scientific research, the microbiome and its wider role in general health and wellness are now very much at the forefront of clinical research, with over 800 peer-reviewed scientific publications on the topic published to date.
How Artificial Intelligence and advanced analytics are delivering value for clinical trials
A MIT study on clinical trial success rates found that the overall probability of success for all drugs and vaccines is 13.8 percent. Two-thirds of trial failures occur due to inadequate efficiency, flawed design, inappropriate end points, or under-enrolment.
Vol 25, No. 05, May 2021
Harnessing the Power of Technology to Build a Fairer, Healthier World
Healthcare is the cornerstone of social and economic development, and of global health security. Building strong health systems is not only an investment in healthier populations, but also an investment in safer and more stable societies. Intrinsic to laying the groundwork for those resilient health systems is harnessing the power of digital technologies, the adoption of which has certainly been accelerated by the COVID-19 pandemic.
Vol 25, No. 04, April 2021
Is digital technology making healthcare safer? - By Michelle Tan Min Shuen
To err is human. Can the same be said for our digital counterparts?
Vol 25, No. 03, March 2021
Your Secrets for Sale - By Michelle Tan Min Shuen

Do existing policies sufficiently protect unsuspecting patients from being preyed upon by third parties for their health data?

Improving Healthcare Access Sustainability in Thailand Through Closer Collaboration - By Joseph Saba

One of Asia’s greatest growth stories, Thailand has moved from a low income to an upper-middle-income nation in less than a generation. In the process, the country has invested in their healthcare ecosystem and introduced a universal healthcare coverage (UHC) program that makes it possible for a large part of the population to access basic health services at little to no cost, contributing to higher life expectancies and lower birth rates.

Vol 25, No. 02, February 2021
Revolutionising Healthcare in the Age of IoT - By Michelle Tan Min Shuen

The convergence of the Internet of Things (IoT) and blockchain technology may just be the next frontiers of digital technology in the healthcare industry.

Vol 25, No. 01, January 2021
The Machines will Heal Us - By Michelle Tan Min Shuen

Addressing the root causes behind AI’s slow adoption rates is the first step towards achieving sustainable development goals for Artificial Intelligence (AI) in healthcare.

AI, The Missing Puzzle Piece in Accelerating Clinical Decisions - By Peter Quinlan

Clinicians have a heavy responsibility; their decisions turn information into actions. Today, there is a growing need for innovation in clinical decision making. COVID-19 has shown us that in emergency situations, these critical decisions can be the difference between life and death. With chronic diseases are on the rise, healthcare systems are under pressure to deliver better care to more people at lower cost.

A Tale of Two Specimens in Precision Oncology

Will liquid biopsy replace tissue biopsy for genomic alterations profiling?

What’s next for Telehealth in APAC? - by Tim Morris

Telehealth adoption has accelerated during the pandemic as clinics and hospitals had to turn away non-essential consultations to mitigate the risk of infections, and reduce the burden on the healthcare workforce.

Securing Telemedicine Platforms in an Evolving Threat Landscape - by George Lee

There are areas of our lives and society that might not go back to exactly the way they were before the pandemic – from reconfiguring workspaces to accommodate a distributed workforce, to contactless delivery and dining experiences, to planning our future travels based on new dynamics of social distancing. Along with these changes is the increasing adoption of telehealth or telemedicine.

Battling Climate Change with Artificial Intelligence - by Deborah Seah

Despite its large carbon footprint and high amounts of waste generated every year, the tech industry might just be the solution to the world’s climate change problems. Enter artificial intelligence with all its potential, researchers and companies have leveraged on this technology to assist in finding solutions to help combat or mitigate the effects of climate change.

Next Stop: SPACE - by Deborah Seah

Commercial space flight for space tourism might seem costly and far from an ordinary individual’s reach. However, over the past decade, the commercial space sector has been growing slowly but surely with private companies looking to launch its own commercial space flight with private passengers. Here we take a look at what has been done so far and what does the future look like for space tourism.

COVID-19 Vaccine Development: What does it take? - By Deborah Seah

The race for a vaccine against COVID-19 continues as the number of confirmed cases across the world continue to escalate. Vaccine development is known to be a rigorous process of testing together with strict regulatory rules over many years before commercialization. But what will it take to condense the usual trial period and yet preserving the necessary testing for safety and efficacy?

COVID-19 Vaccine Platforms: The Top 5 and How They Work - By Deborah Seah

Crippling healthcare systems, high unemployment rates, and a pile of societal issues, these account for only a portion of the damage done since the start of the COVID-19 pandemic in early 2020. Only time will tell which candidate vaccine will pull us out of the woods as research institutes and biotech companies race to develop a viable vaccine against the novel disease.

Impact of COVID-19 Crisis on the Environment - By Deborah Seah

With its multi-faceted strike on many industries and countries across the world, the COVID-19 pandemic has undoubtedly tested the preparedness and resilience of governments and healthcare systems alike. But is there a sliver-lining for the environment as a result of the global outbreak?

Precision Oncology

Patient selection for PARP inhibitor treatment in BRCA- & HRR-associated cancers.

COVID-19 Diagnostic Kits: The Singapore Story

Singapore-based companies and research institutes contribute to the fight against COVID-19 through development of diagnostic test kits for COVID-19 testing.

Digitising Primary Healthcare Services in Singapore - By Michelle Tan Min Shuen

Private and public partnerships are essential for the successful implementation of healthcare strategies. Technology should not be seen as an inhibitor, but rather an enabler, towards reaching worldwide healthcare goals.

The Modern Hospital Network and its Role in Patient Care

Justin Chiah, Senior Director, South East Asia, Taiwan and Hong Kong/Macau (SEATH) and Product Category, Asia Pacific Japan (APJ) for Aruba, a Hewlett Packard Enterprise Company deep dives into the crucial roles of a hospital's network for patient care.

Eko.ai: Changing the Game for Echocardiography

Interview with Dr Carolyn Lam co-founder of eko.ai.

High Mortality, Low Probability: The Lesser Known Dangers of Nipah Virus

First emerged in 1998 in Malaysia, the Nipah virus was found to be transmissible from animals to humans with an estimated case fatality rate of 40 to 75 percent.1 Despite not having any more cases within Malaysia and Singapore it is still present in various parts of Bangladesh and India. With high fatality rate and currently no treatment or vaccine available, there is a pressing need to boost research and development in the area.

China Market Access for MedTech via Hong Kong and the Greater Bay Area Initiative

The stringent regulatory requirements in Mainland China can be overly onerous for many MedTech manufacturers looking to sell into one of the world's largest and fastest growing healthcare markets. By contrast, Hong Kong's certification requirements for imported MedTech devices are voluntary and, in any case, less burdensome provided the manufacturer has already obtained certification in their home country.

Don't Panic, Be Cautious, and Together We Can Stop the Coronavirus Epidemic!

Supplementary charts submitted by Professor Lawrence Lau and Professor Yanyan Xiong.

CytoMed Therapeutics - Pioneer in Advancing Cellular Immunotherapy against Cancer

First incorporated in 2018, CytoMed Therapeutics is a start-up spin-off from the Agency for Science, Technology and Research (A*STAR). Its main focus is to leverage on their proprietary technologies to develop "off-the-shelf" immunotherapeutics for a wide range of cancers.

Asia needs to wake up to the threat of peripheral artery disease

The incidence of PAD is rising four times faster in Asia than Europe, if left untreated, PAD can lead to strokes, heart attacks, lower limb amputations complications caused by restricted blood flow and clots.

TurtleTreeLabs — Changing the Course of the Dairy Industry

Food tech start-up based in Singapore leverages on cell-based methods to address impact of dairy industry on the environment.

Combination Therapy for Hepatocellular Carcinoma

Presenting their results at the ESMO Asia Congress in 2019, researchers of the IMbrave150 study show for the first time in a decade a new class of treatment for hepatocellular carcinoma. The study reveals phase III trial results of a form of combination immunotherapy comprising of the PD-L1 inhibitor atezolizumab and the VEGF inhibitor bevacizumab.

Sustainability in Healthcare Financing

Commentary by Professor David E. Bloom, a Clarence James Gamble Professor of Economics and Demography at Harvard T.H. Chan School of Public Health on health care finance and its sustainability.

MiRXES - A Game Changer in MicroRNA Applications

Local Singapore-based biotech company, MiRXES Pte Ltd, spun off from the Agency for Science, Technology and Research (A*STAR) in Singapore in 2014. Their microRNA research and technology platform looks to be applied across a range of biotech uses with a current focus on diagnostic tools for disease detection.

Game Changers

Established in 2015, NDR Medical Technology is a medical device company which focuses on leveraging artificial intelligence technology to help improve clinical outcomes during surgery.

Epidemiology of Factors associated with Low Muscle Mass in Elderly
By Deborah Seah

In a collaborative research, funded by the Singapore Economic Development Board, Changi General Hospital, and Abbott, the first part of the SHIELD study aimed to identify factors that are associated with muscle mass loss in community-dwelling elderly Singaporeans, through a cross-sectional study.

Low Glycaemic Index Foods for Healthier Diets

Singapore-based company, Nuvojoy offer low glycaemic index alternatives to favourite Asian desserts. Clinically-tested products such as premixes for soy pudding, kueh bahulu, and kueh lapis were developed by Nuvojoy in their journey to provide healthy alternatives for the Asian palate.

Disruptive Technologies in the Tobacco Industry
By Dr. Tan Kok Kuan

The recent outbreak of vaping related lung illnesses in the US, some even leading to death, has thrown into doubt the safety of e-cigarettes, once hailed to be the answer to the smoking epidemic.

Empowering the consumer in heart health management

How will digital health technologies help to tackle the number one cause of the death worldwide?

Game Changers

Triple-Threat Start-up Technology to shake up both Food and Biomedical industries

The Lab Report

Researchers from National University of Singapore looking to discover novel metal-based anti-cancer drugs with reduced toxicity.

Single cell multi-omics and AI are powering the next generation of precision medicine

Tumour diversity is what makes cancer so difficult to treat, but scientists and doctors are starting to address the issue through the use of single cell technologies. Two emerging technologies, AI and multiomics single cell measurements, will play a key role.

Supporting Children with Low Vision

The journey of iC2 PrepHouse and their motivations in creating programmes to help children with low vision.

China's New Drug Administration Law Frames a Promising Regulatory Landscape

Four years after the initiation of an extensive regulatory reform to accelerate new drug approvals, the Chinese legislature finally passed the new Drug Administration Law (DAL) on August 26, 2019, which will become effective as of December 1, 2019.

Preterm Births? Diet not the only answer

Hearing from an expert on nutrition from DSM Nutritional Products on prevention of preterm births.

The key in diagnosis and treatment

Commemorating International Day of Radiology with insights to a leading company in Radiology

Tackling Antimicrobial Resistance

The number of deaths caused by antimicrobial resistance is projected to reach 10 million people yearly by 2050. This will translate into significant impact on public health and world economies if measures are not taken.

Clinical research studies pave the way for better healthcare

Studies provide insight to metabolic disease in Singapore through deep phenotyping and medical imaging.

Up in the Clouds with Artificial Intelligence and Healthcare

How cloud computing services help to boost businesses in creating artificial intelligence applications for healthcare.

Understanding aspects and applications of Harm Reduction in Asia

Consideration of harm reduction policies and products to avert the negative effects of addictive consumption of harmful substances.

On the edge of an AI revolution: unlocking its full potential and maintaining regulatory balance

With the rapid pace at which AI is increasingly being utilised in healthcare systems we need to evaluate how far we have come, where to improve, and prepare for the future.

How Artificial Intelligence (AI) will shape the future of precision diagnosis

The future of medical diagnosis is not a competition between AI and clinicians. It is about AI extending the capabilities of doctors to help them get diagnosis right the first time, and to deliver more personalized care.

New Artificial Intelligence (AI) based system predicts risks of major cardiac events for clinical triage

The AITRIAGE technology, which uses biological parameters to calculate patients' risk score within minutes, could transform patient management in the emergency department.

Healing with Technology

Physical rehabilitation is a branch of medicine aimed to enhance and restore the functional ability of those with physical impairments or disabilities. Present practices in physical rehabilitation are mostly labor - intensive. In this article will shall delve into the world of robotics and its potential in physical rehabilitation.

Smart Hospital: An Instrument of Care

A Look at How Smart Technologies Save More Lives and Improve Patients' Experience

Artificial Intelligence (AI) in Precision Cancer Diagnostics: Myth or Magic?

Experts from ACT Genomics will walk us through current AI developments and applications in precision cancer diagnostics

Transforming Healthcare with Data and Artificial Intelligence

AI can transform healthcare at every touchpoint, but clinicians and researchers need to first address their data infrastructure to meet computing needs in research and treatment.

Are we close to finding a cure for HIV?

Why is it so difficult to treat HIV? Will there ever be a cure for HIV? Hear from Cal Cohen.

Collective wisdom in action

Experts at ACT Genomics and Bumrungrad International Hospital shed insight on the current practice of molecular tumour boards in the Asia Pacific

Xencor leukemia trial - hope for leukemia?

Recently, the Food and Drug Administration (FDA) has lifted its partial hold on the Xencor leukemia trial after the incident involving two deaths a few months back. In agreement with the FDA, Xencor stated that it has made changes to the study protocol, increasing monitoring and clinical management standards to avoid future similar cases. By Lim Wan Er

Dawn of the full genome era in Asia

How would knowing the secret to our genes help consumers, businesses, and the healthcare industry as a whole? by Dr. Iri Sato-Baran

The journey towards a smoke-free future

Tobacco Heating System a better alternative for smokers than cigarettes. by Professor Manuel Peitsch

An update on lung cancer treatments in 2019

Dr. Tan Chee Seng gives an update on the latest breakthrough in advanced non-small cell lung cancer treatments.

The lightsaber of radiation therapy

This technologically advanced method of radiotherapy delivery can destroy cancer with painless and precise radiation beams. by Dr. David Tan

Liquid biopsies and its implications on Asia

The most recent advancements in liquid biopsies for cancer management are reviewed in this article. Dr Liisa and Dr Allen tell us more.

Making precision oncology a reality

Advancements in genomic profiling and the evolution of regulatory science is making precision oncology a wider reality for all patients. by Dr James Creeden

Water woes: Fast-approaching global water calamity

The water we rely on is being clogged fast by prescription drug waste, chemicals used in agriculture and industry, and micro-plastics, and it is seeping into the public water chain to threaten human health and wellbeing. by David Noble

Asia's daunting tuberculosis problem

Drug-resistant tuberculosis is poised to be a growing public health crisis, especially affecting low and middle-income countries. by Dr. Raph Hamers

When milk turns sour

A miniaturised paper-based kit for milk freshness analysis by the determination of alkaline phosphatase levels. by Kuldeep Mahato and Dr. Pranjal Chandra

Healthcare in Asia is about to be disrupted by mobile technology

Clinical mobility is transforming care at healthcare facilities around the world and is having a profound impact on nurses, doctors, IT executives and patients. By Chris Sullivan

Breast cancer - It's not just one cancer

This article talks about the different types of breast cancer present in women and treatment options available.

Is 3D printed food the taste of the future?

3D food printing offers a range of benefits, but can it replace the traditional methods we all know and love?

Staying ahead of the healthcare game in Asia

Collaboration between healthcare leaders in the public and private sectors through funding and various training avenues is what will help the medical industry overcome their challenges

Three medical imaging trends to watch in 2019

Imagine the future of healthcare

Breast cancer: Men get it too

This understudied male breast cancer accounts for around one percent of all breast cancers worldwide

Feeding the sea

Revolutionising aquaculture: A new food source for fish & shrimp with natural marine algae

Asian oncologists' perception in adopting next-generation sequencing multigene panels

Most oncologists feel that genomic testing is useful, but not all would order a test for their patients. The experts at ACT Genomics tell us more.

Time to get serious

Thierry Protas looks at the effect of the Drug Supply Chain Security Act (DSCSA) legislation on companies looking to export pharma products to the United States, the looming 2018 cut off point for compliance, and how coding and marking is a key consideration.

Delivering on the promise of digital health

The role of patient-level digital interventions in improving patient outcomes across the Asia Pacific region. By Rowena Yeo

Rehabilitation in good hands

From pre-programmed software to intention detection application, soft robotic medical technologies have it all to become the future of rehabilitation for patients with neurological disorders. By Jane Wang

Gene edited foods: Key to solving the world's food crisis

Scientists say the technology could be used one day to increase yields and drought and pest resistance, and improve nutrient proles. By Melita Brainta

The food revolution

3D printing has become a phenomenon in recent years. With an extensive history and many variations of it, 3D printers have permeated various manufacturing industries, and surprisingly, even the food industry. Tan Guan Chwen explores 3D printing and food printing.

The future of pharma: Digital, personalized, and dynamic

Find out how new cancer medicines are being made, starting with dogs. By Andrew Hessel

Using real world evidence in the development of new medicine

Learn about the differences between real world data and real world evidence. By Andrew Roddam and Sumitra Shantakumar

Hunting for new drugs to treat mental illness

Dr Anil K. Ratty and Dr Michael Entzeroth speak on the landscape of mental illness in Asia and the road to solving a burgeoning issue

Clean cow starts now

Most of us are familiar with the two most commonly heard gases in the air we inhale and exhale - oxygen and carbon dioxide. Less attention is given to methane, one of the many gases in the ozone. By Lim Wan Er

How to make value-based care a reality?

Healthcare providers today face the challenge of delivering up-to-date, evidence-based care given the ever-burgeoning pool of medical evidence, coupled with the hassle of meeting advance electronic health record (EHR) platform integration requirements. Dr Ujjwal Rao proposes that buying knowledge-based CDSS is increasingly more favourable and the way forward.

Impactful interventions to maximise healthspan

In order to design impactful interventions that can maximise the length of time that a person is healthy, we must first understand fundamental research about the biology of ageing. By Dr Anis Larbi

Viral hepatitis in Arkhangai: How Asia's first micro-treatment program's successes can be leveraged to treat a "silent killer"

The Arkhangai Liver Disease Free Program is a first-of-its-kind collaboration project in Asia and has nearly cured all its screened patients - at no cost to them. In light of the rising hepatitis infections in the world, public and private entities should work together to eliminate viral hepatitis.

The long-suffering challenge of vaccination

Most individuals of education and science know how important vaccination is to public health, yet it has seen, and still sees, many challenges. Pearly Neo takes a closer look.

Navigating the screening conundrum in the pharmaceutical industry

Mary O'Loughlin highlights the importance of consistency and compliance in the rapidly changing Asia-Pacific healthcare landscape.

Are boys with asthma more susceptible to bone fractures?

New Australian research shows that asthma may be associated with an increased possibility of childhood bone fractures, especially for boys. By Lim Wan Er

Clinical program for oral immunotherapy for food allergies

Oral immunotherapy for food allergies can bring significant benefits to children with food allergies. It carries risks and has a significant cost. This treatment requires significant commitment from the children and their caregivers, for it to be performed safely and effectively.
by Dr Soh Jian Yi

Humanities for health

Mediating between the disease, the patient, and the physician. By Ivy Chua, Izza Haziqah and Rafiq Ismail

Digital transformation and the rise of smart hospitals

With the Asia-Pacific healthcare market in a period of digital transformation and the explosion in IoT devices, Dirk Dumortier looks at the importance of the network in modernizing healthcare delivery and keeping healthcare provider and patient data safe in the face of cyber threats.

IoT helps healthcare providers deliver the right treatment to the right patient

The healthcare industry faces a myriad of challenges. The traditional way of delivering patient care by dividing their attention between treating patients and handling administrative matters is not sustainable. With technology, doctors and nurses can free up their minds andhands to focus on providing quality service. By George Pepes.

Brain aging in ASEAN

The elderly population in ASEAN countries is rapidly aging, which brings about significant economic, social and fiscal consequences to the region. Brain aging is perhaps one of the most important challenges we will face, as it represents an integral part of our overall health and well being. Dr. Shawn Watson shares about this natural decline in our cognitive capabilities as we age.

What value-based healthcare means for Asia

Value-based healthcare is a healthcare delivery model in which providers, including hospitals and physicians, are paid based on patient health outcomes, which differs from a conventional fee-for-service system where providers are paid based on the treatment services delivered. By Fredrik Nyberg

Improve healthcare access to tackle Asia's healthcare challenge

Hyper-precise technology reinvents how healthcare is delivered. By Karen Reddington

Bringing the Asian cosmetics markets to greater heights

Once a privilege of elites, beauty products are now accessible and enjoyed by the masses. With many brands in the market, consumers are spoilt for choice and have higher expectations, which cosmetics manufacturers are determined to meet. In their quest for competitive advantage, cosmetics manufacturers have created and proposed various novel product claims that consumers and the industry have grown to embrace, Jessen Curpen tells us more.

Meeting the global demand for non-monoclonal antibody biosimilars

Dr Frank Detmers gives us an overview of how new approaches to the manufacture of biosimilars have the potential to support sustainable access to critical non-monoclonal antibody biosimilars such as human growth hormone, follicle stimulating hormone, tissue plasminogen activators and many other protein therapeutics.

CSI: Cancer Scene Investigation

Are there enough clues for us to find the killer?

Improving risk stratification in hypertensive heart disease: What is in the horizon?

Hypertension is a major contributor to heart failure and other cardiovascular complications. Integrating markers of adverse myocardial features (fibrosis and exaggerated hypertrophy) in hypertension management may improve risk stratification and informed therapeutic options for hypertensive patients, says Asst Prof Calvin Woon Loong Chin.

Digital health technology to combat world's number one killer

Diederik Zeven says the key to fighting cardiovascular disease still lies in early detection and leveraging on data and technology to decide on the best treatment strategy tailored for each patient.

Cancer Immunotherapy: where we stand and move forward

Over the past few decades, immunotherapy has been studied intensively as a promising treatment for cancer. Newer types of immune treatments are currently being studied, and they will impact how we treat cancer in the future. Dr Chen Shu-Jen and Dr Poon Song Ling share more with us.

New Womb-Like Invention for Preterm Infants

In some extreme cases, a premature infant might need to be removed from the womb before completing the gestational period. Doctors from The Children's Hospital of Philadelphia in United States designed an innovative Biobag with the idea to allow premature newborns to continue developing in an artificial environment mimicking a mother's womb. The Biobag (Figure 1) used in the experiment is...

Reversing Paralysis: Can I Walk Again?

Rachel's pet kitten pads its way gently to her side, brushing its warm furry body against her legs. "Hello there..." Rachel coos, as her gaze meets those innocent eyes of the kitten glistening like black pearls. The kitten then yawns and stretches, before heading off to explore some nook in Rachel's house. Rachel misses the warm furry feeling against her leg, as with her spinal cord injury, her bottom torso is unable...

The Potential of Saving Human Lives with Hibernation

Humans go into hibernation, something we only read about in science fiction. is this possible? However, Dr Kevin Fong, who was trained in intensive care medicine, brought us through the mysterious tunnel in the Discovery program he hosted at BBC; 'Human Hibernation: The Big Sleep' [1]. In this program, he presented a case happened in 2006 that a Japanese man survived through weeks without food and...

Osimertinib, A New Drug to Extend Life of Advanced Lung Cancer Patients

Lung cancer is a complex disease that can be classified by the types of cells seen under microscope, and also can be described further by mutation-the changes to the cell causing cancer growth [1]. In other words, lung cancer could occur due to the mutation of different kind of genes. Thus far, researchers had identified a few mutations that might be found in lung cancer. These discoveries introduced the era...

Cancer: Fighting an Informed Battle

"14 people die from cancer daily." "1 in 3 Singaporeans die of cancer." "33 people are diagnosed with cancer everyday." [1] These irking numbers and facts are thrown in our way every single day. They unnerve us, frighten us, and prompt us to leap to our feet and start taking control of our health and our lives. While some may disregard these figures, it is the undeniable truth that cancer has indeed...

Biomedical Engineering Industry Alliance (BME IA): Working in Favour of the Industry's Stakeholders

APBN was recently invited to attend the 5th Annual Biomedical Engineering Industry Alliance networking event on 11th November 2016 held in the Shaw Foundation Alumni House in the National University of Singapore. There to welcome us was Dr. Dieter Trau, the original founder of BME IA. He introduced us to the current chairman of the organization, Dr. Michael J.A. Girard, with whom...

Counter-Acting Chemotherapy's Side Effects

We attended the press conference for the release of Akynzeo, the latest anti-nausea and anti-vomiting drug distributed by Mundipharma for chemotherapy patients, led by Dr Wong Seng Weng. A comprehensive virtual reality program explaining the effects of the medication was presented with the Oculus Rift, giving a peek of the potential of technology in educating the public. Akynzeo was...

(Writer's Thought) Treating Patients, Not Diseases

Many trends have evolved in the healthcare industry, such as personalised medicine or alternative medicine...

Top Medical Tourism Hotspots

You may spot a foreigner in Orchard Singapore, and pass him off as a tourist here for holidaymaking. But, no, he is in fact a medical tourist. Indian national Timir Patel, 48, is one such example. He travelled specially from Mumbai to have kidney transplant surgery at Mount Elizabeth Hospital [1]. Singapore, together with India and Thailand are the top 3 Asian countries that medical tourists flock to. These...

The Growing Trend of Medical Spas

Tourists would usually plan an itinerary to go sight-seeing, shop, capture pictures and videos and to relax. Personally, I go travelling to break the routine of the daily grind and to rejuvenate. My other favourite parts of taking a vacation include immersing in another culture, sampling local food, meeting new people and experiencing another way of living, even for a little while...

Eliminating MALARIA. Is it Possible?

"Eeeeee", the familiar high-pitched sound one hears when a mosquito flies near our ears, and we bat it away irritatedly. One of these mosquitoes could be the Anopheles species, which is the carrier of Plasmodium parasites that cause the life-threatening disease, malaria. On World Malaria Day (25 April 2016), World Health Organisation (WHO) released a report stating that, although an ambitious...

Hand, Foot and Mouth Disease: Symptoms, Prevention and Updates on HFMD

Co-organized by the Institute of Molecular and Cell Biology (IMCB), part of the Agency for Science, Technology and Research (A*STAR) Singapore, the Consortium of Hand, Foot, Mouth Disease/Enterovirus 71 Studies in Asia (CoHESIA) and the Singapore Society of Microbiology and Biotechnology (SSMB), an international conference for Hand, Foot and Mouth Disease...

That Gut Feeling: How A Healthy Digestive System Has Everything To Do With It

Due to an average adult's changing and dynamic lifestyle of always chasing time, the easier option is to reach for the convenient and the accessible, which can result to an unhealthy diet, not getting enough sleep or lack of exercise. On top of these, the air we breathe, the food we eat, the things we touch-virtually anything...

World Heart Day - At the Heart of Health

Home is where the heart is. This phrase is not all that figurative as it is biological. As one of the vital organs, the heart has been long identified as the center of the entire body and the seat of life. Founded in 2000, World Heart Day is celebrated in more than 100 countries around the world to raise public awareness about heart health and the prevention of cardiovascular disease...

The Drinkable Book™: A Book You Wouldn’t Mind Getting Wet

It is a given that water is a basic human need. The daily recommendation for optimum health is to drink 8 to 10 glasses of water everyday, as the average adult's body is composed of 75% water. Water serves as an agent to flush out toxins and energize our immune system, which in turn fights off several diseases...

H2O: Managing our Water and Technology

Water, one of the three crucial ingredients in our life sustenance. We can only last for about 3 to 4 days without water. Our body is made of at least 60% water, and it helps keep us functioning daily...

World Toilet Organisation – Let’s Talk about Toilets

When one mentions the acronym, WTO, we would immediately associate it with the World Trade Organisation. Little did many know that we have our very own WTO spearheaded by a Singaporean and the headquarter is also on this sunny island that deals with creating toilets around the world including water management and sanitation...

3D Printing: The Versatile Innovation at the Healthcare Forefront

Additive Manufacturing (AM), more popularly known as 3D printing, was first developed for designers and engineers in 1984 [1] to assemble an object from a virtual design by adding layer by layer of various material like bioplastic tubes until the desired result is complete. This process is done by forging, moulding and...

Healthcare Cost Effectiveness in Singapore

Many countries in Asia are facing an ageing population and the growing demand for healthcare has never been more urgent. Good quality healthcare is expensive, and many of the most-developed nations of the world are finding that the ever-rising costs for quality care are unsustainable. Singapore, on the other hand, has dexterously managed to keep its costs low without sacrificing quality...

Cytosponge: Trailblazer for Barrett's Oesophagus?

When you fall off the wagon from your healthy diet or habitually consume food that trigger heartburn or indigestion, acid reflux may be a common occurrence. However, stomach acid backing up your food pipe is never a pleasant experience. If this happens often, and you're having difficulty swallowing food, it may be best to...

Bending Forwards: Blending Yoga into Our Modern Lifestyle

When touching your toes or reaching for something from a high shelf is proving to be difficult, you probably need to work on your flexibility. Being flexible doesn't necessarily mean turning into a gymnast or a contortionist. Rather, it's being able to...

What to expect in Year 2050

There shall be no surprise to some of the events that we will be witnessing in the next 35 years. Some islands will be completely submerged, some languages and species of animals will be extinct. Changes to our intentional or unintentional habits that are disruptive to the environment...

International Mountain Day: Are we making a mountain out of a molehill?

I believe we've all heard of this idiom: Making a mountain out of a molehill - greatly exaggerating the severity of the situation. In many aspects, the idea of adverse magnification of an issue is surrounding us on a daily basis. With the advent of technology and the use of social media, we are forced to face the bombardment of minor issues that...

Learning to Code may give you a Vanilla Sky – Yuhui N. Lin

I have vivid memories of my first Nintendo hand-held gaming device, the infamous GameBoy. My first input computer language was DOS, where users had to punch the keys 'cd blahblah' and backslashes. It did not take too long till I started programming in Perl, Visual Basic and HTML...

Social Media Literary: One step ahead or one step back? – Clarrie Ng

What comes to mind when you see the words: Social Media? For some, it is an everyday interaction with your phone and for others, you are wary of this term and cannot help but notice its presence everywhere. Just how significant is social media in our daily lives?...

Small, but Powerful. Who are the Rivals? — Yuhui N. Lin

Singapore, renowned for its Monopoly 'Playground' among foreign investors and traders, most often find itself in a competitive position next to China and Japan...

Some Parents don't vaccinate their Children, and why they should stop behaving like a Clown.

Inoculation of infected individuals' skin material was a common procedure before the 1700s. Edward Jenner was one of the pioneers for smallpox vaccine, and Jenner is considered as the Grandfather of Immunology. In simple terms, we should learn that vaccination procedure was not invented by pharmaceutical companies. The main objective of vaccination is to save lives. From a simple inoculation procedure to an in-depth understanding of acquired immunity?, vaccination is considered as the most important medical discovery.

"To edit or not?"- the dilemma around CRISPR.

Now, we are empowered to edit the genome of our offspring - to correct them from inheritable genetic diseases (i.e. Down's syndrome) and if we like, add in one or a few of our desirable traits. This has been made easier with the power of the newly-discovered CRISPR technology. Like other genome editing tools that have long been challenged with bioethical concerns, CRISPR emergence has once again cast unseen anxiety, caution and yet anticipation in the future of translational therapeutics for human diseases.

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